| Purpose: To analyze the epidemic change trend of cancer in Linzhou City from 2010 to 2019.
Methods: The data were derived from the tumor registry in Linzhou City from 2010 to 2019. According to the China Cancer Registration Work Guidance Manual and the data quality evaluation standards of the International Agency for Research on Cancer (IARC) and the International Association of Cancer Registries (IACR), the completeness, validity and reliability of the incidence and death data were evaluated. The incidence or mortality and standardized incidence or mortality were calculated by gender, age and cancer type. The standardized rate was calculated using the age composition of the national census standard population in 2000. The Joinpoint software was used to analyze the trend of incidence and mortality, and calculate the average annual percentage change (AAPC).
Results: From 2010 to 2019, the incidence of cancer in Linzhou City showed a slow upward trend, with an AAPC of 2.09% (95% CI: 0.58% - 3.63%). After adjusting the population age structure, the standardized incidence tended to be stable. The results of the age-group incidence trend showed that the incidence rate remained stable or showed a downward trend between 30 and 79 years old, and the incidence in the age groups of 15-29 years old and over 80 years old showed an upward state. The change in age-group mortality mainly showed a significant increase in those over 80 years old, and other age groups remained in a downward or stable state. The incidence and death situation by site showed that esophageal cancer and gastric cancer in both men and women showed a significant downward trend. The incidence of lung cancer and prostate cancer in men increased year by year, and lung cancer, breast cancer, cervical cancer and thyroid cancer in women increased significantly. The mortality rate of gastric cancer and esophageal cancer in men showed a downward trend, while the mortality rate of malignant tumors such as prostate cancer and pancreatic cancer in men increased significantly, and the mortality rate of ovarian cancer in women also increased significantly.
Conclusion: The incidence of common cancer types such as thyroid cancer, prostate cancer and female breast cancer has increased significantly. The incidence and mortality rates of gastric cancer, liver cancer and esophageal cancer have all shown a slight downward trend. In the future, it is urgent to further strengthen and optimize cancer prevention and control strategies and measures. |
