| Abstract: [Objective] To comprehend the epidemiological characteristics and trends of thyroid cancer in the tumor registration areas of Nanning City, and provide scientific evidence for the government to formulate relevant prevention and treatment strategies. [Methods] The data from the Nanning Cancer Registration that met the quality assessment criteria during the period from 2016 to 2020 were collected and compiled, and the incidence and mortality data of thyroid cancer were selected for analysis.The incidence (mortality) rate, the age-standardized incidence (mortality) rates by Chinese standard population(ASIRC, ASMRC) and world standard population (ASIRW, ASMRW), the cumulative incidence (mortality) rate of the age between 0 and 74 years, and the age-specific incidence (mortality) rate were calculated. The joinpoint regression model was used to estimate the trends of incidence and mortality.. [Results] During the period from 2016 to 2020, a total of 2291 new cases of thyroid cancer were reported in Nanning Cancer Registration. The incidence rate was 7.70/105, with the ASIRC of 7.23/105 and ASIRW of 6.22/105, the cumulative incidence rate of the age between 0 and74 years was 0.59%. The incidence was higher in female than that in male(=731.15, P＜0.05) , and higher in urban areas than that in rural areas(=373.96, P＜0.05). The incidence rate of thyroid cancer began to rise sharply from the 20 years old and declined after peaking in the 50~54 years age group. The incidence rate in female remained at a high level in the age group of 30~59 years old, which was higher than that in male. A total of 121 deaths of thyroid cancer were reported. the mortality rate was 0.41/105, with the ASMRC of 0.32/105, and ASMRW of 0.31/105, the cumulative mortality rate of the age between 0 and 74 years was 0.03%. The mortality rate was higher in female than that in male (=10.77, P＜0.05). The age-specific mortality rate for thyroid cancer showed a wave-like upward trend after the 40 years old and peaked in the 75 - 79 age group.. The incidence rate and ASIRC appeared a tendency towards a rise among the whole population (AAPC=21.11%, t=3.25, P<0.05; AAPC=22.02%, t=3.39, P<0.05) , male (AAPC=19.45%, t=4.35，P<0.05; AAPC=19.81%，t=5.74，P<0.05) and Urban areas (AAPC=30.62%, t=7.13, P<0.05; AAPC=32.38%, t=7.25, P<0.05) in Nanning cancer registration areas. The mortality rate and ASMRC in the Urban areas (AAPC=43.06%, t=7.73, P<0.05; AAPC=47.63%, t=8.60, P<0.05) showed an increasing trend. [Conclusions] The incidence rate of thyroid cancer in cancer registration areas of Nanning City showed an upward trend from 2016 to 2020. Urban areas should be the key regions for prevention and control , and women of childbearing age and menopausal women should be the high - risk groups. |
