2020年甘肃省肿瘤登记地区胰腺癌流行特征及2010-2020年变化趋势分析
Epidemiological characteristics of pancreatic cancer and its change trend from 2010 to 2020 in tumor registration areas of Gansu Province
投稿时间:2024-10-14  修订日期:2025-02-19
DOI:
中文关键词:  胰腺癌  流行特征  变化趋势  甘肃
英文关键词:Pancreatic cancer  Epidemic characteristics  Changing trend  Gansu
基金项目:中国消化道早癌医师共同成长计划科研项目(GTCZ-2022-GS-62-0004)
作者单位邮编
孙倩 甘肃省武威肿瘤医院 733000
胡军国 甘肃省武威肿瘤医院 733000
刘玉琴* 甘肃省肿瘤医院 730000
叶延程 甘肃省武威肿瘤医院 733000
蔡清华 甘肃省武威肿瘤医院 733000
王宏宗 甘肃省武威肿瘤医院 733000
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中文摘要:
      摘要 目的:分析甘肃省肿瘤登记地区2020年胰腺癌发病和死亡情况及2010-2020年变化趋势。方法:整理2010-2020年甘肃省肿瘤登记地区胰腺癌的数据,计算胰腺癌的粗发病(死亡)率、标化发病(死亡)率、0-74岁累积率。用Joinpoint 4.7.0软件计算2010-2020年甘肃省肿瘤登记地区胰腺癌中标率的年度变化百分比(APC)。结果:2020年甘肃省肿瘤登记地区共报告胰腺癌发病838例,发病粗率为6.52/10万,中标发病率和世标发病率分别为4.03/10万、4.49/10万,占所有恶性肿瘤总发病数的2.50%;2020年甘肃省肿瘤登记地区共报告胰腺癌死亡702例,粗死亡率为5.46/10万,中标死亡率和世标死亡率分别为3.25/10万、3.73/10万,占所有恶性肿瘤总死亡数的3.98%。2010-2020年甘肃肿瘤登记地区共报告胰腺癌发病2413例,占甘肃省所有恶性肿瘤的1.90%。胰腺癌粗发病率为5.28/10万,中标发病率为4.18/10万,世标发病率为4.63/10万,0-74岁累积率为0.49%。2010-2020年甘肃肿瘤登记地区共报告胰腺癌死亡1871例,占甘肃省所有恶性肿瘤的2.38%,胰腺癌粗死亡率为3.92/10万,中标死亡率为3.09/10万,世标死亡率为3.50/10万,0-74岁累积率为0.36%。2010-2020年甘肃肿瘤登记地区胰腺癌发病率和死亡率都表现为44岁以下处于较低水平,45岁开始明显上升的趋势。从中标率数据来看,2010-2020年甘肃省胰腺癌发病率呈升高趋势,APC为0.411%,变化趋势的差异无统计学意义(P>0.05)。2010-2020年甘肃省胰腺癌死亡率亦呈升高趋势,APC为6.515%,变化趋势差异有统计学意义(P=0.014<0.05)。结论:甘肃省胰腺癌防控情势严峻,2010-2020年甘肃省胰腺癌发病率和死亡率均呈现逐年升高的趋势,发病率和死亡率都是男性高于女性,农村高于城市,农村地区中老年男性人群是胰腺癌防治的重点人群,需开展有针对性的防控措施。
英文摘要:
      Abstract Objective To analyze the incidence and death of pancreatic cancer in 2020 and the change trend from 2010 to 2020 in tumor registration areas of Gansu Province. Methods The crude incidence rate, standardized incidence rate and cumulative rate of pancreatic cancer aged 0-74 years were calculated by sorting out the data of pancreatic cancer in the tumor registration areas of Gansu Province from 2010 to 2020. Joinpoint 4.7.0 software was used to calculate the annual percentage change (APC) in the successful rate of pancreatic cancer in the tumor registry area of Gansu Province from 2010 to 2020. Results In 2020, a total of 838 cases of pancreatic cancer were reported in the tumor registration areas of Gansu Province, with a coarse incidence rate of 652/100 000, the bid-winning incidence rate and the world-standard incidence rate were 403/100 000 and 4.49/100 000 respectively, accounting for 2.50% of the total incidence of all malignant tumors. In 2020, 702 cases of pancreatic cancer deaths were reported in the tumor registration areas of Gansu Province, with the crude mortality rate of 5.46/100,000, the bid mortality rate and the world standard mortality rate of 3.25/100,000 and 3.73/100,000, respectively, accounting for 3.98% of the total deaths of all malignant tumors. From 2010 to 2020, a total of 2413 cases of pancreatic cancer were reported in tumor registration areas in Gansu province, accounting for 1.90% of all malignant tumors in Gansu Province. The crude incidence of pancreatic cancer was 5.28/100 000, the bid incidence was 4.18/100 000, the world standard incidence was 4.63/100 000, and the cumulative rate of 0-74 years old was 0.49%. From 2010 to 2020, a total of 1871 pancreatic cancer deaths were reported in the tumor registration areas of Gansu Province, accounting for 2.38% of all malignant tumors in Gansu province. The crude mortality rate of pancreatic cancer was 3.92/ 100 000, the bid mortality rate was 309/100 000, the world standard mortality rate was 3.50/ 100 000, and the cumulative rate of 0-74 years old was 0.36%. From 2010 to 2020, the incidence and mortality of pancreatic cancer in the tumor registration areas of Gansu showed a low level under the age of 44, and a significant upward trend at the age of 45. From the data of winning bid rate, the incidence of pancreatic cancer in Gansu Province showed an increasing trend from 2010 to 2020, and the APC was 0.411%, with no statistical significance in the change trend (P > 0.05). From 2010 to 2020, the mortality rate of pancreatic cancer in Gansu Province also showed an increasing trend, and the APC was 6.515%, with statistical significance (P=0.014 < 0.05). Conclusion The prevention and control situation of pancreatic cancer in Gansu Province is serious. From 2010 to 2020, the incidence and mortality of pancreatic cancer in Gansu Province show an increasing trend year by year. The incidence and mortality are higher in males than females and higher in rural areas than in urban areas.
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