2020年河南省食管癌流行现况及2010-2020年变化趋势分析
Incidence and Mortality of Esophageal Cancer in Henan in 2020 and Trend of Changes from 2010 to 2020
投稿时间:2024-07-30  修订日期:2024-08-16
DOI:
中文关键词:  食管癌  发病率  死亡率  变化趋势  河南
英文关键词:esophageal cancer  incidence  mortality  trend  Henan
基金项目:国家重点研发计划政府间国际科技创新合作重点专项(2021YFE0106000)
作者单位邮编
韩靖远 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
冯晨曦 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
陈琼 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
徐慧芳 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
刘茵 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
郭肖利 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
王潇杨 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
刘红伟 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
王红 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
张韶凯* 河南省肿瘤医院 郑州大学附属肿瘤医院 450008
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中文摘要:
      [目的]分析2020年河南省食管癌发病和死亡情况及2010~2020年变化趋势。[方法]基于河南省各肿瘤登记处上报的符合质量标准的数据,以性别和城乡为分层依据,分别计算2020年食管癌粗发病率和粗死亡率、标化发病率和标化死亡率。利用Joinpoint软件计算年度变化百分比(annual percent change,APC),和平均年度变化百分比(average annual percent change,AAPC),分析2010-2020年食管癌发病与死亡的变化趋势。[结果]据估计,2020年河南省食管癌新发病例26700例,粗发病率为24.38/10万,中标率为17.5/10万,世标率为17.6/10万;2020年河南省估计食管癌死亡病例数为20988例,粗死亡率19.16/10万,中标率为13.14/10万,世标率为13.08/10万。农村地区中标发病率是城市地区的1.79倍、死亡率是城市地区的1.68倍。男性中标发病率是女性的1.81倍、死亡率是女性的2.01倍。年龄别发病率和年龄别死亡率均是40岁开始迅速上升,分别至80~84岁年龄组和85+年龄组达峰值。2010-2020年河南省肿瘤登记地区食管癌中标发病率和中标死亡率总体呈显著下降趋势(AAPC分别为-5.70%和-4.73%,P均<0.05)。[结论]河南省食管癌疾病负担较为严重,呈现性别差异和城乡差异。近十年河南省发病率和死亡率呈显著下降趋势,但仍然高于全国平均水平。未来应重点加强一级预防与二级预防策略的实施,以减轻食管癌带来的健康负担。
英文摘要:
      [Purpose]To estimate the incidence and mortality of esophageal cancer in Henan Province in 2020 and the trend of changes from 2010 to 2020. [Methods]Based on quality-standard-compliant data reported by various cancer registries in Henan Province, crude incidence and mortality rates, as well as age-standardized incidence and mortality rates for esophageal cancer in 2020 were calculated, stratified by gender and urban-rural residence. Joinpoint software was used to calculate the annual percent change (APC) and average annual percent change (AAPC) to analyze trends in esophageal cancer incidence and mortality from 2010 to 2020. [Results]It is estimated that in 2020, there were 26,700 new cases of esophageal cancer in Henan Province, with a crude incidence rate of 24.38/105 population, an age-standardized incidence rate by Chinese standard population (ASRC) of 17.5/105, and an age-standardized incidence rate by world standard population (ASRW) of 17.6/105.The estimated number of esophageal cancer deaths in Henan Province for 2020 was 20,988, with a crude mortality rate of 19.16/105 population. The age-standardized mortality rate by Chinese standard population (ASMRC) was 13.14/105, and the age-standardized mortality rate by world standard population (ASMRW) was 13.08/105. The ASRC incidence rate in rural areas was 1.79 times that of urban areas, while the mortality rate was 1.68 times higher. The ASRC incidence rate for males was 1.81 times that of females, and the mortality rate was 2.01 times higher. Both age-specific incidence and mortality rates began to rise rapidly from age 40, reaching peak values in the 80-84 age group and 85+ age group, respectively. From 2010 to 2020, the ASRC incidence and mortality rates of esophageal cancer in cancer registration areas of Henan Province showed a significant downward trend overall (with AAPC of -5.70% and -4.73%, respectively, both P<0.05). [Conclusion]The disease burden of esophageal cancer in Henan Province is relatively severe, showing gender and urban-rural disparities. Over the past decade, the incidence and mortality rates in Henan Province have shown a significant downward trend, but they still remain higher than the national average. Future efforts should focus on strengthening the implementation of primary and secondary prevention strategies to reduce the health burden caused by esophageal cancer.
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