2013-2017年南通市胆囊癌流行现状、变化趋势与生存分析
Epidemic Status, Trends and Survival Analysis of Gallbladder Cancer in Nantong from 2013 to 2017
投稿时间:2024-02-20  修订日期:2024-04-13
DOI:
中文关键词:  胆囊癌  流行  趋势  生存分析  江苏
英文关键词:gallbladder cancer  epidemic  trend  survival analysis  Jiangsu
基金项目:南通市卫生健康委科研课题(QN2023046)
作者单位邮编
蔡娟 南通市疾病预防控制中心 226007
徐红 江苏省疾病预防控制中心 210009
楚楚 南通市疾病预防控制中心 226007
韩颖颖* 南通市疾病预防控制中心 226007
赵春燕 南通市疾病预防控制中心 226007
林玲 南通市疾病预防控制中心 226007
韩亚蓉 南通市疾病预防控制中心 226007
王宇琦 南通市疾病预防控制中心 226007
蔡波 南通市疾病预防控制中心 226007
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中文摘要:
      摘 要:[目的] 分析2013-2017年南通市胆囊癌的流行现状、变化趋势和生存情况。[方法] 收集2013-2017年南通市胆囊癌发病和死亡数据,分性别、年龄和城乡计算发病率和死亡率,应用Joinpoint软件对胆囊癌的发病和死亡进行趋势分析,分别采用寿命表法和EdererⅡ法计算观察生存率和相对生存率。[结果] 2013-2017年南通市胆囊癌发病率和死亡率分别为6.36/10万和4.91/10万;中标发病率和中标死亡率分别为2.62/10万和1.94/10万。2013-2017年南通市胆囊癌的发病率、死亡率和中标死亡率均呈现出逐年上升趋势(P<0.05)。男性和女性中标发病率分别为2.43/10万和2.83/10万;男性和女性中标死亡率分别为1.74/10万和2.16/10万,女性均高于男性。平均发病年龄为70.33岁,发病年龄中位数为72岁。城市和农村发病中标率分别为2.40/10万和2.69/10万,死亡中标率分别为1.61/10万和2.05/10万,农村均高于城市。农村地区胆囊癌的发病率、死亡率和中标死亡率均呈现出逐年上升趋势(P<0.05)。5年观察生存率为12.90%,5年相对生存率为14.47%,5年观察生存率和相对生存率均呈现出逐年上升趋势(P<0.05)。[结论]建议以农村地区和中老年女性为重点关注对象,采取有针对性的防控措施,加强综合防治能力,从而降低胆囊癌的发病率和死亡率,提升患者生存率。
英文摘要:
      Abstract: [Purpose] To analyze the incidence and mortality, trends, and survival of gallbladder cancer in Nantong from 2013 to 2017. [Methods] The gallbladder cancer incidence and mortality data from 2013 to 2017 were collected from Nantong cancer registries. The incidence and mortality were calculated by gender, age and urban and rural areas. Joinpoint software was used to analyze the incidence and mortality trends of gallbladder cancer. The observed survival rate and relative survival rate were calculated by using life table method and Ederer II method respectively. [Results] From 2013 to 2017, the gallbladder cancer incidence and mortality rates were 6.36/105 and 4.91/105 , respectively; the age-standardized incidence and mortality rates by Chinese standard population in 2000 (ASIRC,ASMRC) were 2.62/105 and 1.94/105 , respectively. The crude incidence and mortality , and ASMRC showed an increasing trend (P<0.05). The ASIRC for male and female was 2.43/105 and 2.83/105 respectively; The ASMRC for male and female was 1.74/105 and 2.16/105, respectively, with ASIRC and ASMRC in female being higher than those in male. The average age of onset is 70.33 years old, and the median age of onset is 72 years old. The ASIRC in urban and rural areas was 2.40/105 and 2.69/105, respectively, and the ASMRC was 1.61/105 and 2.05/105, respectively. ASIRC and ASMRC in Rural areas were higher than those in urban areas. The crude incidence and mortality rate and ASMRC of gallbladder cancer in rural areas showed an increasing trend (P<0.05). The 5-year observed survival rate was 12.90%, and the 5-year relative survival rate was 14.47%. Both the 5-year observed survival rate and relative survival rate showed an increasing trend (P<0.05).[Conclusion]It is suggested that targeted prevention and control measures should be taken to strengthen the comprehensive prevention and control capacity of gallbladder cancer in Nantong, focus on rural areas and middle-aged and elderly women, reduce the incidence rate and mortality of gallbladder cancer in Nantong, and improve the survival rate of patients.
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