侯新燕,张江霞,李 丹.超声和钼靶X线诊断乳腺癌的临床价值比较[J].中国肿瘤,2013,22(3):198-201.
超声和钼靶X线诊断乳腺癌的临床价值比较
A Comparison of Clinical Value Between Ultrasonography and Mammography in the Diagnosis for Breast Cancer
投稿时间:2012-11-09  
DOI:10.11735/j.issn.1004-0242.2013.03.A2012321
中文关键词:  乳腺癌  超声  钼靶X线
英文关键词:breast cancer  ultrasonography  mammography
基金项目:
作者单位
侯新燕 北京军区总医院 
张江霞 北京军区总医院 
李 丹 北京军区总医院 
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中文摘要:
      摘 要:[目的] 探讨年龄和肿块大小对超声和钼靶X线在乳腺癌筛查及检查中的影响。[方法] 所有受检者在同一天接受超声和钼靶X线检查,检查中详细记录病变位置、大小及声像图特征,由超声专业和放射专业的高年资医师在双盲情况下,独立作出诊断。[结果] 共1 090例乳腺病例1 132个病灶,其中病理诊断乳腺癌301例314个病灶,良性病变789例818个病灶。早期乳腺癌诊断率为53.50%。超声检查乳腺癌的灵敏度为95.22%,特异性为65.16%,假阴性率为4.78%;钼靶X线检查乳腺癌的灵敏度为90.13%,特异性为86.31%,假阴性率为9.87%,二者之间的差异具有统计学意义(P<0.05)。超声与钼靶X线联合检查的灵敏度为97.77%,特异性为92.42%。对于<50岁女性,钼靶X线的灵敏度低于超声,二者间差异具有统计学意义(P<0.05)。≥50岁女性的超声和钼靶X线的灵敏度相似,其差异无统计学意义(P>0.05)。在肿块直径6~10mm组中钼靶X线灵敏度最低,与超声的灵敏度比较差异有统计学意义(P<0.05)。[结论] 在乳腺癌检查中,对于≥50岁女性,超声和钼靶X线具有相同的检查效果,而<50岁女性,超声检查乳腺癌的灵敏度优于钼靶X线。当肿块直径在6~10mm时钼靶X线灵敏度最低。
英文摘要:
      Abstract:[Purpose] To explore the influence of ultrasonography and mammography based on the women’s age and breast cancer tumor size in breast cancer screening and diagnosis. [Methods] All patients were examined by ultrasonography and mammography in the same day. The lesion location,size and imaging features were recorded. Diagnosis was made independently by senior physician of ultrasound and radiography professional in the double blind manner. [Results] In 1 132 lesions of 1 090 cases,314 breast cancer lesions of 301 cases and 818 benign foci of 789 cases were confirmed by pathology. The sensitivity,specificity,false negative rate were 95.22%,65.16%,4.78% for ultrasonography and 90.13%,86.31%,9.87% for mammography,respectively. The differences between the ultrasonography and mammography were statistically significant (P<0.05). The sensitivity and specificity were 97.77% and 92.42% for joint ultrasonography and mammography. Mammography had a lower sensitivity than ultrasonography in women younger than 50 years,whereas the sensitivity of ultrasonography was similar to mammography in women older than 50 years. The sensitivity in the mass 6~10mm group was lowest for mammography that had significant difference compared with ultrasonography (P<0.05). [Conclusions] The sensitivity of ultrasonography is greater than that of mammography in women younger than 50 years in breast cancer examination. Ultrasonography has a similar effect with mammography in women older than 50 years. The sensitivity was lowest for mammography in patients with the mass 6~10mm.
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